The Model for End-stage Liver Disease (MELD) scoring system aims at stratifying recipients by their disease severity according to a score
estimating the 3-month probability of death on the waiting list.
A high MELD indicates severe illness, thus a candidate in urgent need of
transplantation and vice versa. Candidates are stratified in a descending order starting with the highest MELD. The calculation of an individual’s MELD score is based on three objective lab parameters, i.e.
MELD was developed by the Organ Procurement and Transplantation network (OPTN)/United Network for Organ Sharing (UNOS) and implemented in February 2002. The Eurotransplant Board decided in 2003 to implement MELD for liver allocation in Eurotransplant.